MRI1 — Methylthioribose-1-phosphate isomerase 1
MRI1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
MRI1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Mitochondrial Dynamics Mitochondrial & OxPhos | ATP5MC1, ECHS1, EDF1, FIS1, FRA10AC1, HIGD2A, IFNAR2, MICOS13 +2 more |
About the gene
| Synonyms | MGC3207, MRDI, mtnA, Ypr118w |
|---|---|
| Chromosome | 19: 13764522-13774282 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Predicted intracellular proteins |
| Molecular function | Isomerase |
| Biological process | Amino-acid biosynthesis, Methionine biosynthesis |
Function
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.