SCUBA

MTIF2 — Mitochondrial translational initiation factor 2

MTIF2 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

MTIF2's module in each cell type

Cell typeModuleShares the module with
ColonocytesMitochondrial Peroxisomal Metabolism
Mitochondrial & OxPhos
ACO1, AGPS, ALDH9A1, AP1M2, CAAP1, CCDC47, CDS1, FAM120A +15 moreView in SCUBA

About the gene

SynonymsIF-2mt
Chromosome2: 55236595-55269347
Predicted locationIntracellular
Essential geneYes
Protein classEssential proteins, Predicted intracellular proteins
Molecular functionInitiation factor
Biological processProtein biosynthesis

Function

One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.