NDUFV3 — NADH:ubiquinone oxidoreductase subunit V3
NDUFV3 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
NDUFV3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | DNA Damage Repair DNA/chromatin regulation | ANKRD10, ASF1A, DDX18, DNAJC17, ENPP5, KLRC4, KLRD1, NARS1 +15 more | |
| Macrophages | Ribosome Biogenesis Housekeeping | ABCE1, BCCIP, CLPX, COX20, DDX18, DUS1L, EIF3B, IDH3A +17 more | View in SCUBA |
About the gene
| Synonyms | CI-10k |
|---|---|
| Chromosome | 21: 42879644-42913304 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins |
| Biological process | Electron transport, Respiratory chain, Transport |
Function
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. May be the terminally assembled subunit of Complex I
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.