NTSR1 — Neurotensin receptor 1
NTSR1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
NTSR1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Monocytes | MET Tissue Repair Tissue homeostasis | BIN1, CXXC5, EMP2, EVA1C, JRK, MET, MPRIP, RHPN1 +3 more | View in SCUBA |
About the gene
| Synonyms | NTR |
|---|---|
| Chromosome | 20: 62708836-62762771 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | G-protein coupled receptors, Predicted membrane proteins, Transporters |
| Molecular function | G-protein coupled receptor, Receptor, Transducer |
Function
G-protein coupled receptor for the tridecapeptide neurotensin (NTS). Signaling is effected via G proteins that activate a phosphatidylinositol-calcium second messenger system. Signaling leads to the activation of downstream MAP kinases and protects cells against apoptosis.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.