SCUBA

OPLAH — 5-oxoprolinase, ATP-hydrolysing

OPLAH belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

OPLAH's module in each cell type

Cell typeModuleShares the module with
ColonocytesGlycan Precursor Biosynthesis
Nutrient processing
ANXA7, APEH, ASL, ATP2A3, CC2D1A, CCDC124, CCND3, CLIC3 +30 moreView in SCUBA

About the gene

Synonyms5-Opase, OPLA
Chromosome8: 144051266-144063965
Predicted locationIntracellular
Essential geneNo
Protein classDisease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins
Molecular functionHydrolase

Function

Catalyzes the cleavage of 5-oxo-L-proline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.