PDCD11 — Programmed cell death 11
PDCD11 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PDCD11's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | DNA Repair Housekeeping Housekeeping | ACBD6, CD320, DDX10, DUS1L, EEF1D, EIF3G, FAAP20, FARSA +15 more | View in SCUBA |
About the gene
| Synonyms | ALG-4, KIAA0185, NFBP, RRP5 |
|---|---|
| Chromosome | 10: 103396626-103446294 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Plasma proteins, Predicted intracellular proteins |
| Biological process | rRNA processing |
Function
Essential for the generation of mature 18S rRNA, specifically necessary for cleavages at sites A0, 1 and 2 of the 47S precursor. Directly interacts with U3 snoRNA. Involved in the biogenesis of rRNA
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.