SCUBA

EEF1D — Eukaryotic translation elongation factor 1 delta

EEF1D belongs to a gene co-expression module in 9 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

EEF1D's module in each cell type

Cell typeModuleShares the module with
CD8⁺ T cellsTranslation Elongation
RNA processing & translation
EEF1A1, EEF2, EIF3E, NDFIP1, PFDN5, RACK1, TOMM7, VSIRView in SCUBA
Gamma-delta T cellsTranslation Initiation
RNA processing & translation
BTF3, C12orf57, COMMD6, COX4I1, COX7C, EEF1B2, EEF1G, EIF3E +18 more
Glial cellsRNA Translation Processing
RNA processing & translation
CYCS, EEF1B2, HNRNPA1, HNRNPH3, LDHA, NAP1L1, NPM1, PFDN5 +5 moreView in SCUBA
Goblet cellsPyroptosis Stress Response
Stress
ADAM15, AURKAIP1, CDC37, CENPX, COMTD1, DDX39A, GSDMD, INF2 +6 moreView in SCUBA
Innate lymphoid cellsProtein Biogenesis & Import
Protein processing & ER
ANAPC16, ATP6AP2, CD164, COMMD6, KLRB1, NACA, PFDN5, S100A4 +6 moreView in SCUBA
MacrophagesTranslation Initiation
Housekeeping
AKR1B1, CAMLG, CAPZB, EEF2, EID1, EIF3D, EIF3E, EIF3F +26 moreView in SCUBA
Mucosal-associated invariant T cellTranslation Elongation
RNA processing & translation
BAX, BTF3, COX4I1, EEF1B2, EIF3K, FAU, FTL, GPX4 +8 more
Natural Killer cellsTranslation Elongation
RNA processing & translation
BTF3, COMMD6, EEF1A1, EEF1B2, EIF3E, NACA, NOP53, PFDN5 +3 moreView in SCUBA
Smooth muscle cellsTranslation elongation housekeeping
Housekeeping
COX4I1, EEF1A1, EEF2, FTH1, FTL, GAPDH, PTMA, RACK1 +4 moreView in SCUBA

About the gene

SynonymsEF-1D, FLJ20897
Chromosome8: 143579697-143599541
Predicted locationIntracellular
Essential geneNo
Protein classPlasma proteins, Predicted intracellular proteins
Molecular functionDNA-binding, Elongation factor
Biological processProtein biosynthesis, Transcription, Transcription regulation

Function

EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP, regenerating EF-1-alpha for another round of transfer of aminoacyl-tRNAs to the ribosome. Regulates induction of heat-shock-responsive genes through association with heat shock transcription factors and direct DNA-binding at heat shock promoter elements (HSE)

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.