PEX26 — Peroxisomal biogenesis factor 26
PEX26 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PEX26's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Senescent Colonocyte Identity Senescence & shedding | AAK1, APPL2, BTNL3, BTNL8, C1orf115, C2CD2L, CTDSP2, HHLA2 +10 more | View in SCUBA |
About the gene
| Synonyms | FLJ20695 |
|---|---|
| Chromosome | 22: 18077923-18105396 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters |
| Biological process | Protein transport, Transport |
Function
Peroxisomal docking factor that anchors PEX1 and PEX6 to peroxisome membranes. PEX26 is therefore required for the formation of the PEX1-PEX6 AAA ATPase complex, a complex that mediates the extraction of the PEX5 receptor from peroxisomal membrane.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.