C1ORF115 — Chromosome 1 open reading frame 115
C1ORF115 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
C1ORF115's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | EC Quiescence Identity Endothelial cell development | ABCC4, ARHGAP5, ENPP4, FAM107A, GIT2, IFNAR2, LRRFIP1, MSI2 +8 more | View in SCUBA |
| Enterocytes | Amino acid absorption Absorption | ACE2, CREB3L3, FAM3C, SELENOP, SLC15A1, SLC6A19, TOR1AIP2 | View in SCUBA |
| Pericytes | Vascular Barrier Integrity Migration & adhesion | FAM107A, GIMAP1, GIMAP4, GIMAP7, ITGB4, JAM2, MYCT1, NRN1 +2 more | View in SCUBA |
About the gene
| Synonyms | FLJ14146, RDD1 |
|---|---|
| Chromosome | 1: 220690363-220699153 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
Regulates drug efflux through modulation of ABCB1 localization and activity.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.