POLR2H — RNA polymerase II, I and III subunit H
POLR2H belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
POLR2H's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Innate lymphoid cells | Transcription RNA Processing RNA processing & translation | ARMCX6, BANF1, CCAR1, CLDND1, COMMD1, FEZ2, HELZ, HSBP1 +11 more | View in SCUBA |
About the gene
| Synonyms | RPB8 |
|---|---|
| Chromosome | 3: 184361710-184368596 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins |
| Molecular function | DNA-binding |
| Biological process | Transcription |
Function
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.