CLDND1 — Claudin domain containing 1
CLDND1 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CLDND1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Inflammatory effector Immune regulation | C3AR1, CAST, CMTM3, CREB3L2, EIF4E3, EPB41, FYCO1, IL18R1 +9 more | View in SCUBA |
| CD8⁺ T cells | Effector Memory CD8 T cell maturation | DENND2D, GIMAP1, GIMAP4, GIMAP7, GPR183, GZMK, ITM2C, KLRG1 +3 more | View in SCUBA |
| Innate lymphoid cells | Transcription RNA Processing RNA processing & translation | ARMCX6, BANF1, CCAR1, COMMD1, FEZ2, HELZ, HSBP1, IRF2 +11 more | View in SCUBA |
| Macrophages | NRF2 Oxidative Stress Stress | ACOT9, AHRR, ARMC9, BASP1, CARD19, CCDC71L, CD226, CTNNBL1 +27 more | View in SCUBA |
| Natural Killer cells | ILC1/NK Cytotoxic Cytotoxicity | A1BG, CASK, EIF3G, GZMK, ITM2C, KLRB1, NCF1, PDCD4 +4 more | View in SCUBA |
About the gene
| Synonyms | C3orf4, Z38 |
|---|---|
| Chromosome | 3: 98497912-98523066 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins, Transporters |
Function
Plays a role in negatively regulating the permeability of cells to small molecules
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.