PPP1R14D — Protein phosphatase 1 regulatory inhibitor subunit 14D
PPP1R14D belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PPP1R14D's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Arp2/3 Actin Branching Cytoskeletal | ACTR3, ANXA4, ARHGDIA, ARPC1B, ARPC2, ARPC4, ARPC5, ATP6V1D +30 more | View in SCUBA |
About the gene
| Synonyms | CPI17-like, FLJ20251, GBPI-1, MGC119014, MGC119016 |
|---|---|
| Chromosome | 15: 40815451-40828709 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | Protein phosphatase inhibitor |
Function
Inhibitor of PPP1CA. Has inhibitory activity only when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.