ANXA4 — Annexin A4
ANXA4 belongs to a gene co-expression module in 7 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ANXA4's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | Cytoskeleton/motility migration & adhesion | ANXA2, BHLHE41, C4orf48, CAPG, CAPN2, CIB1, ISCU, LGALS1 +11 more | View in SCUBA |
| Enterocytes | Mature colonocyte metabolism Nutrient metabolism | ASS1, ATP1B3, BTNL3, CORO2A, HMCN2, MGAT4A, MOB3B, MTUS1 +6 more | View in SCUBA |
| Gamma-delta T cells | Cytotoxic Effector Program cytotoxicity | ADGRG1, CADM1, CX3CR1, FCGR3A, FGFBP2, FGL2, GNLY, GZMB +14 more | |
| Glial cells | Glial Neuroprotective Response Neroprotection | CYB5A, DPYSL3, DRAP1, FADS2, IGFBP4, MDK, NBDY, NDUFB2 +4 more | View in SCUBA |
| Lymphatic endothelial | Vascular Lumen Formation endothelial development | BLCAP, CD47, GINM1, LMAN1, MTDH, RASIP1, STAT1 | View in SCUBA |
| Macrophages | Inflammatory Monocyte Activation Inflammatory | ACTN1, ADAM8, AGTRAP, ANXA2, C15orf48, CD44, CD9, DRAM1 +21 more | View in SCUBA |
| Mucosal-associated invariant T cell | Cytotoxic Effector cytotoxicity | CCM2, CD320, CST7, DYNLRB1, GZMM, LIMD2, MCUB, MGMT +10 more |
About the gene
| Synonyms | ANX4 |
|---|---|
| Chromosome | 2: 69644425-69827112 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins |
Function
Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.