PRIMA1 — Proline rich membrane anchor 1
PRIMA1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PRIMA1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Glial cells | Basement Membrane Adhesion ECM remodeling | ANTXR2, C2orf88, CHL1, DMD, GPC1, ITGAV, TMEM123 | View in SCUBA |
About the gene
| Synonyms | PRIMA |
|---|---|
| Chromosome | 14: 93718298-93788485 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Predicted membrane proteins |
| Biological process | Neurotransmitter degradation |
Function
Required to anchor acetylcholinesterase (ACHE) to the basal lamina of the neuromuscular junction and to the membrane of neuronal synapses in brain. Also able to organize ACHE into tetramers (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.