PRND — Prion like protein doppel
PRND belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PRND's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Inflammatory Angiogenesis ECM remodeling | ADM, APOD, CHST15, CMTM3, GPIHBP1, GRAP, HOMER3, LOX +7 more | View in SCUBA |
About the gene
| Synonyms | dJ1068H6.4, DOPPEL, DPL, PrPLP |
|---|---|
| Chromosome | 20: 4721909-4728460 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Predicted membrane proteins, Transporters |
| Molecular function | Prion |
| Biological process | Fertilization |
Function
Required for normal acrosome reaction and for normal male fertility (By similarity). Can bind Cu(2+).
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.