SCUBA

PSMD9 — Proteasome 26S subunit, non-ATPase 9

PSMD9 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

PSMD9's module in each cell type

Cell typeModuleShares the module with
Gamma-delta T cellsmRNA Splicing & Trafficking
RNA processing & translation
ARF1, ARL6IP1, ARRDC2, B3GNT2, C17orf49, CCDC12, CWC15, DDX39A +19 more

About the gene

Synonymsp27, Rpn4
Chromosome12: 121888732-121918297
Predicted locationIntracellular
Essential geneNo
Protein classPlasma proteins, Predicted intracellular proteins
Molecular functionChaperone

Function

Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC). During the base subcomplex assembly is part of an intermediate PSMD9:PSMC6:PSMC3 module, also known as modulator trimer complex; PSMD9 is released during the further base assembly process

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.