CWC15 — CWC15 spliceosome associated protein homolog
CWC15 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CWC15's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | mRNA Splicing & Trafficking RNA processing & translation | ARF1, ARL6IP1, ARRDC2, B3GNT2, C17orf49, CCDC12, DDX39A, EIF5A +19 more | |
| Innate lymphoid cells | ER-Golgi Trafficking Protein processing & ER | ATP2B1, ATP6V1D, CAPZA2, CGGBP1, CNOT4, COPS5, CRIPT, CSTB +15 more | View in SCUBA |
About the gene
| Synonyms | AD002, C11orf5, Cwf15, HSPC148 |
|---|---|
| Chromosome | 11: 94962620-94973586 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Predicted intracellular proteins |
| Biological process | mRNA processing, mRNA splicing |
Function
Involved in pre-mRNA splicing as component of the spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable).
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.