ARRDC2 — Arrestin domain containing 2
ARRDC2 belongs to a gene co-expression module in 6 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ARRDC2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | Notch signaling Intercellular communication | ARL4D, HES1, ICOSLG, IRS2, KLF4, MXI1, NRARP, PMEPA1 +2 more | View in SCUBA |
| Gamma-delta T cells | mRNA Splicing & Trafficking RNA processing & translation | ARF1, ARL6IP1, B3GNT2, C17orf49, CCDC12, CWC15, DDX39A, EIF5A +19 more | |
| Macrophages | Anti-inflammatory Response Inflammatory | AMPD2, BHLHE40, CBX4, CDKN1B, CEBPD, CITED2, DENND3, EIF4B +31 more | View in SCUBA |
| Monocytes | Immediate Early Activation Stress | GALR2, IER5L, MRPL55, MTSS1, NDUFA12, NXT1, RRAS, SLC7A7 +3 more | View in SCUBA |
| Mucosal-associated invariant T cell | TGF-beta Response Immune regulation | ABCA1, ARL4C, CD48, DDX47, DNLZ, ERGIC1, FMNL1, HYPK +21 more | |
| Natural Killer cells | Circadian Innate Signaling Inflammation | CRY1, ITPRIP, MGAT4A, NOCT, PTPRE, SLC15A4, TRAPPC10, UAP1 +1 more | View in SCUBA |
About the gene
| Synonyms | CLONE24945, PP2703 |
|---|---|
| Chromosome | 19: 18001132-18014102 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.