RILP — Rab interacting lysosomal protein
RILP belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
RILP's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Lysosomal Lipid Stress Stress | ADTRP, BAK1, BLOC1S1, CORO1B, CORO2A, DHCR24, FUT2, GDPD3 +14 more | View in SCUBA |
About the gene
| Synonyms | FLJ31193 |
|---|---|
| Chromosome | 17: 1646145-1649866 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Biological process | Protein transport, Transport |
Function
Rab effector playing a role in late endocytic transport to degradative compartments. Involved in the regulation of lysosomal morphology and distribution. Induces recruitment of dynein-dynactin motor complexes to Rab7A-containing late endosome and lysosome compartments. Promotes centripetal migration of phagosomes and the fusion of phagosomes with the late endosomes and lysosomes.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.