CORO1B — Coronin 1B
CORO1B belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CORO1B's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | IgA plasma cell B cell maturation | AIM2, CD27, IGHA1, IGHA2, JCHAIN, MGAT4A, OSBPL10, RASSF6 +2 more | View in SCUBA |
| CD4⁺ T cells | TCR signaling activation TCR/AP1/NFKb pathway | CNST, DAPP1, ECI1, FAAH2, FCMR, GPCPD1, KLHL24, MLLT3 +8 more | View in SCUBA |
| Gamma-delta T cells | Actin-based Motility Cytoskeletal | APBB1IP, CD58, COMMD7, CTSD, EVL, FDFT1, HMOX2, OSTF1 +13 more | |
| Macrophages | Complex I / NADH Dehydrogenase Mitochondrial & OxPhos | AHCY, ANP32A, ANTKMT, APEX1, ARL2, ATIC, ATP5F1A, ATP5ME +31 more | View in SCUBA |
| Monocytes | Mitochondrial Immune Regulation Mitochondrial & OxPhos | CALHM2, DNASE2, DOK2, NDUFAF3, SIGLEC10, SLC39A1, UCP2 | View in SCUBA |
About the gene
| Synonyms | coronin-2 |
|---|---|
| Chromosome | 11: 67435510-67443821 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins |
| Molecular function | Actin-binding |
Function
Regulates leading edge dynamics and cell motility in fibroblasts. May be involved in cytokinesis and signal transduction (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.