RNASE4 — Ribonuclease A family member 4
RNASE4 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
RNASE4's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Monocytes | Monocyte-DC Differentiation Developmental | FBN2, FLT3, GASK1B, HAL, KLHL8, MACIR, MAOA, MARCHF1 +1 more | View in SCUBA |
About the gene
| Synonyms | RAB1 |
|---|---|
| Chromosome | 14: 20684560-20701216 |
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted secreted proteins |
| Molecular function | Antibiotic, Antimicrobial, Endonuclease, Hydrolase, Nuclease |
Function
Cleaves preferentially after uridine bases. Has antimicrobial activity against uropathogenic E.coli (UPEC). Probably contributes to urinary tract sterility.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.