RTKN — Rhotekin
RTKN belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
RTKN's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Pre-mRNA Splicing RNA processing & translation | ATXN7L3B, HNRNPDL, ING5, NPRL3, PRPF38B, RBFA, SREK1, SRSF11 +4 more | View in SCUBA |
About the gene
| Synonyms | B5 |
|---|---|
| Chromosome | 2: 74425835-74442422 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Biological process | Apoptosis |
Function
Mediates Rho signaling to activate NF-kappa-B and may confer increased resistance to apoptosis to cells in gastric tumorigenesis. May play a novel role in the organization of septin structures.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.