SRSF11 — Serine and arginine rich splicing factor 11
SRSF11 belongs to a gene co-expression module in 7 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SRSF11's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD8⁺ T cells | Chromatin RNA Processing RNA processing & translation | CHD4, EIF4G2, FLNA, GNB1, MTDH, SFPQ, UBXN4, ZNF207 | View in SCUBA |
| Gamma-delta T cells | Centrosome Organization DNA/chromatin regulation | AKAP9, ARMCX6, CCNT2, CEP350, CUL5, DDHD1, DDX42, DENND6A +23 more | |
| Glial cells | Glial RNA Homeostasis RNA processing & translation | ATRX, DYNC1H1, GTF2I, NCL, RBM25, SCN9A, SYNM | View in SCUBA |
| Innate lymphoid cells | Transcription RNA Processing RNA processing & translation | ARMCX6, BANF1, CCAR1, CLDND1, COMMD1, FEZ2, HELZ, HSBP1 +11 more | View in SCUBA |
| Macrophages | RNA Processing Housekeeping Housekeeping | BAZ1A, BDP1, CCAR1, CCDC88A, CLIP1, CUL5, DHX36, DNM1L +32 more | View in SCUBA |
| Mucosal-associated invariant T cell | TGF-β Immune Regulation Immune regulation | ADAM12, AFF1, AKAP9, FNBP4, IKZF3, INPP4A, MAN1A1, NSD3 +8 more | |
| Neutrophils | Proteostasis RNA Metabolism Housekeeping | APP, HNRNPD, MTDH, PSMB7, RIF1, SLC44A1, STT3B, TMEM87A |
About the gene
| Synonyms | NET2, p54, SFRS11 |
|---|---|
| Chromosome | 1: 70205682-70253052 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Plasma proteins, Predicted intracellular proteins |
| Molecular function | RNA-binding |
| Biological process | mRNA processing, mRNA splicing |
Function
May function in pre-mRNA splicing
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.