SAP30BP — SAP30 binding protein
SAP30BP belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SAP30BP's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | RNA Splicing Regulation Housekeeping | ABCF1, CDC42SE1, CDC5L, CDV3, CEBPZ, DNAJC7, DYNC1LI1, FGFR1OP2 +13 more | View in SCUBA |
About the gene
| Synonyms | HCNGP, HTRG, HTRP |
|---|---|
| Chromosome | 17: 75667251-75708062 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Predicted intracellular proteins |
| Molecular function | Repressor |
| Biological process | Transcription, Transcription regulation |
Function
Plays a role in transcriptional repression by promoting histone deacetylase activity, leading to deacetylation of histone H3. May be involved in the regulation of beta-2- microglobulin genes (By similarity). (Microbial infection) Involved in transcriptional repression of HHV-1 genes TK and gC
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.