SART1 — Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP
SART1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SART1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | T Cell Migration migration & adhesion | BCL2, BPNT2, CCDC88B, DNM2, EDC4, GMDS, LRRC58, MARK3 +14 more |
About the gene
| Synonyms | Ara1, HAF, SNRNP110, Snu66 |
|---|---|
| Chromosome | 11: 65961728-65980137 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins |
| Biological process | mRNA processing, mRNA splicing |
Function
Plays a role in mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the spliceosome. May also bind to DNA
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.