GMDS — GDP-mannose 4,6-dehydratase
GMDS belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
GMDS's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | T Cell Migration migration & adhesion | BCL2, BPNT2, CCDC88B, DNM2, EDC4, LRRC58, MARK3, MDFIC +14 more | |
| Goblet cells | Goblet Secretory Identity Mucus production & secretion | ARFIP2, C12orf57, CREB3L4, FRZB, HID1, HSPA2, KCNMA1, LRRC26 +8 more | View in SCUBA |
About the gene
| Synonyms | GMD, SDR3E1 |
|---|---|
| Chromosome | 6: 1623806-2245605 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Predicted intracellular proteins |
| Molecular function | Lyase |
Function
Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.