SLC39A4 — Solute carrier family 39 member 4
SLC39A4 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SLC39A4's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Enterocyte lipid metabolism Lipid metabolism | CYP4F2, DHDH, GPX4, MS4A10, OCIAD2, PCK1, PHYH, PLIN2 +3 more | View in SCUBA |
About the gene
| Synonyms | AEZ, AWMS2, ZIP4 |
|---|---|
| Chromosome | 8: 144409742-144416844 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters |
| Biological process | Ion transport, Transport, Zinc transport |
Function
Selective transporter that mediates the uptake of Zn(2+). Plays an essential role for dietary zinc uptake from small intestine (By similarity). The Zn(2+) uniporter activity is regulated by zinc availability. Also exhibits polyspecific binding and transport of Cu(2+), Cd(2+) and possibly Ni(2+) but at higher concentrations.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.