PLIN2 — Perilipin 2

PLIN2 belongs to a gene co-expression module in 10 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

PLIN2's module in each cell type

Cell type	Module	Shares the module with
CD4⁺ T cells	Integrin Rap1 Signaling migration & adhesion	ARL3, ATP2B4, ATXN1, DR1, GDE1, GNA15, GRAMD1B, GTDC1 +8 more	View in SCUBA
CD8⁺ T cells	Heat Shock Response Stress	DNAJA4, DNAJB1, DNAJB4, HSPA1A, HSPA1B, HSPA6, HSPB1, RGS2 +3 more	View in SCUBA
Endothelial	Lipid Droplet Hypoxia Stress	BNIP3, CEMIP2, CNN3, FCGRT, FGD6, SNTB2, TSPAN4	View in SCUBA
Enterocytes	Enterocyte lipid metabolism Lipid metabolism	CYP4F2, DHDH, GPX4, MS4A10, OCIAD2, PCK1, PHYH, SAT2 +3 more	View in SCUBA
Gamma-delta T cells	ER Stress Response Stress	ATP1B3, ATP2A2, BACH1, CPD, EIF2AK3, FAM118A, G3BP2, GRK5 +13 more
Hematopoietic progenitor cells	ER Protein Folding Housekeeping	ASRGL1, CALR, CD63, CHPT1, EMP3, GLUL, HSPA5, IDH2 +13 more
Innate lymphoid cells	Innate Stress Signaling Inflammation	C19orf25, DNAJC15, IFI16, KIF5B, KRCC1, MAP2K6, PCMTD1, RALBP1 +7 more	View in SCUBA
Lymphatic endothelial	NRF2 Oxidative Stress Stress	ATP1B3, F3, GCLM, GRPEL1, HMOX1, SLC3A2, TXNRD1	View in SCUBA
Macrophages	Monocyte Lipid Metabolism Lipid metabolism	ATP13A3, CEP170, CHIC2, COQ10B, CSGALNACT2, ENOSF1, HIPK2, HMGXB3 +14 more	View in SCUBA
Neutrophils	Glycolytic Metabolism Housekeeping	CSTB, CTSD, ENO1, FAM210A, GAPDH, GRN, GSTO1, LDHA +4 more

About the gene

Synonyms	ADFP, ADRP
Chromosome	9: 19108375-19149290
Predicted location	Intracellular
Essential gene	No
Protein class	Metabolic proteins, Plasma proteins, Predicted intracellular proteins

Function

Structural component of lipid droplets, which is required for the formation and maintenance of lipid storage droplets

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.