OCIAD2 — OCIA domain containing 2
OCIAD2 belongs to a gene co-expression module in 7 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
OCIAD2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Leukocyte adhesion signaling migration & adhesion | ARHGDIB, BIN1, CD37, DGKA, DGKZ, EIF3F, EIF3L, EIF4B +22 more | View in SCUBA |
| Endothelial | Inflammatory Angiogenesis Inflammation | AZIN1, DHH, FBLN5, FILIP1L, GJA5, ITSN2, NUDT4, PIK3C2B +6 more | View in SCUBA |
| Enterocytes | Enterocyte lipid metabolism Lipid metabolism | CYP4F2, DHDH, GPX4, MS4A10, PCK1, PHYH, PLIN2, SAT2 +3 more | View in SCUBA |
| Gamma-delta T cells | Mitochondrial Ribosome Mitochondrial & OxPhos | APEX1, APRT, EIF3M, EXOSC5, FAM162A, LSM7, MRPL24, MZT2A +10 more | |
| Goblet cells | Actin Dynamics Cytoskeletal | ABRACL, CD24, CFL1, MYL12A, NDUFB4, NDUFS5, PIN4, RTRAF +3 more | View in SCUBA |
| Innate lymphoid cells | Lipid & Isoprenoid Metabolism Metabolism | ARL6IP1, CHCHD5, ECH1, FDPS, GTF2H5, LYPLA1, NECAP2, NUBP2 +8 more | View in SCUBA |
| Pericytes | Pericyte Identity Developmental | AIF1L, ALPL, ARL15, ASRGL1, EDN1, FAM89A, GFOD1, LPCAT2 +1 more | View in SCUBA |
About the gene
| Synonyms | MGC45416 |
|---|---|
| Chromosome | 4: 48885019-48906937 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins |
Function
Has an essential role in the assembly of mitochondrial respiratory chain complex III. Is also required for STAT3 activation and plays a role in cell migration
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.