SNTA1 — Syntrophin alpha 1
SNTA1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SNTA1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Smooth muscle cells | Costameric cytoskeleton Cytoskeletal | ACTR2, AOC3, APLP2, CTDSPL, FLNC, GNG11, HSPG2, KANK2 +4 more | View in SCUBA |
About the gene
| Synonyms | LQT12, SNT1, TACIP1 |
|---|---|
| Chromosome | 20: 33407957-33443763 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins |
| Molecular function | Actin-binding, Calmodulin-binding |
Function
Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the extracellular matrix via the dystrophin glycoprotein complex. Plays an important role in synapse formation and in the organization of UTRN and acetylcholine receptors at the neuromuscular synapse. Binds to phosphatidylinositol 4,5-bisphosphate (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.