SCUBA

TBC1D32 — TBC1 domain family member 32

TBC1D32 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

TBC1D32's module in each cell type

Cell typeModuleShares the module with
EnterocytesSerotonergic receptor signaling
Secretion
HTR4, KCNQ3, LAMB1, LIMA1, NECTIN3, NFIBView in SCUBA

About the gene

SynonymsbA57L9.1, BROMI, C6orf170, C6orf171, dJ310J6.1, FLJ30899, FLJ34235
Chromosome6: 121079494-121334745
Predicted locationIntracellular, Membrane
Essential geneNo
Protein classPredicted intracellular proteins, Predicted membrane proteins
Molecular functionDevelopmental protein

Function

Required for high-level Shh responses in the developing neural tube. Together with CDK20, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to Shh signaling (By similarity)

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.