TIMM10B — Translocase of inner mitochondrial membrane 10B
TIMM10B belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TIMM10B's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Autophagy Stress Response Stress | AKIRIN1, BRD9, CDKN2AIP, DHX36, DNAJB2, FOXO3, MLXIP, ODF2L +11 more |
About the gene
| Synonyms | FXC1, TIM10B, Tim9b |
|---|---|
| Chromosome | 11: 6481501-6484681 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Biological process | Protein transport, Translocation, Transport |
Function
Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as the external driving force. In the TIM22 complex, it may act as a docking point for the soluble 70 kDa complex that guides the target proteins in transit through the aqueous mitochondrial intermembrane space
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.