CDKN2AIP — CDKN2A interacting protein
CDKN2AIP belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CDKN2AIP's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | RNA processing RNA processing | AARSD1, ABHD14A, AMD1, CALM2, CHMP1B, FRAT1, HNRNPAB, HNRNPDL +7 more | View in SCUBA |
| Gamma-delta T cells | Autophagy Stress Response Stress | AKIRIN1, BRD9, DHX36, DNAJB2, FOXO3, MLXIP, ODF2L, PPP2R2A +11 more | |
| Glial cells | Hypoxia mTOR Stress Stress | AMD1, CITED2, DDIT4, HEXIM1, HSPA2, IFRD1, INTS6, NEU1 +3 more | View in SCUBA |
About the gene
| Synonyms | CARF, FLJ20036 |
|---|---|
| Chromosome | 4: 183444635-183449064 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | RNA-binding |
Function
Regulates DNA damage response in a dose-dependent manner through a number of signaling pathways involved in cell proliferation, apoptosis and senescence.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.