TIMM44 — Translocase of inner mitochondrial membrane 44
TIMM44 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TIMM44's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | DNA Repair Housekeeping Housekeeping | ACBD6, CD320, DDX10, DUS1L, EEF1D, EIF3G, FAAP20, FARSA +15 more | View in SCUBA |
About the gene
| Synonyms | TIM44 |
|---|---|
| Chromosome | 19: 7926718-7943667 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Plasma proteins, Predicted intracellular proteins |
| Biological process | Protein transport, Translocation, Transport |
Function
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner (By similarity). Recruits mitochondrial HSP70 to drive protein translocation into the matrix using ATP as an energy source (By similarity).
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.