TIMM50 — Translocase of inner mitochondrial membrane 50
TIMM50 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TIMM50's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Mitochondrial Translation Mitochondrial & OxPhos | ALG3, APRT, ATP5MC1, BOLA3, C9orf152, CD99, DCXR, DHRS4L2 +32 more | View in SCUBA |
About the gene
| Synonyms | TIM50, TIM50L |
|---|---|
| Chromosome | 19: 39480412-39493785 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins |
| Molecular function | RNA-binding |
| Biological process | Protein transport, Translocation, Transport |
Function
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro; however such activity may not be relevant in vivo. May participate in the release of snRNPs and SMN from the Cajal body
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.