BOLA3 — BolA family member 3
BOLA3 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
BOLA3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | Mitochondrial Translation Mitochondrial & OxPhos | MRPL20, MRPL36, MRPS34, PDCD5, POLR2I, PSMA3, PSMB5, RPL26L1 +2 more | View in SCUBA |
| Goblet cells | Mucosal Innate Defense Immune function | CTSS, DMBT1, ENO1, GPI, LGALS3BP, OLFM4, PIGR, PLA2G2A +4 more | View in SCUBA |
| Macrophages | Mitotic Spindle Assembly Cell cycle | ACTL6A, AKR7A2, ANP32E, BUB3, CCDC167, CENPW, CENPX, DCTPP1 +34 more | View in SCUBA |
About the gene
| Chromosome | 2: 74135400-74147912 |
|---|---|
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins |
Function
Acts as a mitochondrial iron-sulfur (Fe-S) cluster assembly factor that facilitates (Fe-S) cluster insertion into a subset of mitochondrial proteins. Probably acts together with NFU1.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.