TMEM214 — Transmembrane protein 214
TMEM214 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TMEM214's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Glycan Precursor Biosynthesis Nutrient processing | ANXA7, APEH, ASL, ATP2A3, CC2D1A, CCDC124, CCND3, CLIC3 +30 more | View in SCUBA |
About the gene
| Synonyms | FLJ20254 |
|---|---|
| Chromosome | 2: 27032910-27041694 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins, Transporters |
| Biological process | Apoptosis |
Function
Critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis. Required or the activation of CASP4 following endoplasmic reticulum stress
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.