TMIGD3 — Transmembrane and immunoglobulin domain containing 3
TMIGD3 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TMIGD3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | Antimicrobial Oxidative Defense Antibacterial | ADAMDEC1, ALDOA, APOL3, CALHM6, CLEC10A, COX16, CPVL, DEFA5 +30 more | View in SCUBA |
| Monocytes | Tissue-Resident Macrophage Lysosomal & pahgocytosis | AP2A2, BLVRB, CD163, FAH, FCGRT, HTRA1, MKKS, MYO7A +6 more | View in SCUBA |
About the gene
| Synonyms | AD026 |
|---|---|
| Chromosome | 1: 111483348-111563962 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Predicted membrane proteins |
Function
Plays a suppressive role in osteosarcoma malignancy by inhibiting NF-kappa-B activity
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.