TPST1 — Tyrosylprotein sulfotransferase 1
TPST1 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TPST1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Neural-crest Fibroblast Developmental | AMIGO2, C1orf54, CENPW, DCLK1, FLRT2, FOXP2, IGFBP4, KIAA0408 +8 more | View in SCUBA |
| Neutrophils | Granulopoiesis Transcriptional Developmental | EXT1, KLHL2, MAML3, PDE3B, PHF21A, SIPA1L2, STAT5B |
About the gene
| Synonyms | TANGO13A |
|---|---|
| Chromosome | 7: 66205317-66420543 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Predicted intracellular proteins |
| Molecular function | Transferase |
Function
Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.