TUBGCP2 — Tubulin gamma complex associated protein 2
TUBGCP2 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TUBGCP2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | Actin Cytoskeleton Organization Cytoskeletal | ACTR3, ARF1, ARHGDIA, ARPC4, CDC42, DERL1, EIF4G2, GARS1 +20 more | View in SCUBA |
About the gene
| Synonyms | GCP2, SPBC97, Spc97p |
|---|---|
| Chromosome | 10: 133278635-133318823 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins |
Function
Component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation. The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation. Plays a role in neuronal migration.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.