EIF4G2 — Eukaryotic translation initiation factor 4 gamma 2
EIF4G2 belongs to a gene co-expression module in 12 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
EIF4G2's module in each cell type
About the gene
| Synonyms | DAP5, NAT1, p97 |
|---|---|
| Chromosome | 11: 10797050-10808940 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Plasma proteins, Predicted intracellular proteins |
| Molecular function | Initiation factor, Repressor |
| Biological process | Protein biosynthesis, Translation regulation |
Function
Appears to play a role in the switch from cap-dependent to IRES-mediated translation during mitosis, apoptosis and viral infection. Cleaved by some caspases and viral proteases.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.