UBTD1 — Ubiquitin domain containing 1
UBTD1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
UBTD1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Endothelial Cell Migration migration & adhesion | CISD1, CTHRC1, GALNT1, MARCKS, MARCKSL1, NARF, PHLDB2, RHOJ +5 more | View in SCUBA |
About the gene
| Synonyms | FLJ11807 |
|---|---|
| Chromosome | 10: 97498924-97571206 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
May be involved in the regulation of cellular senescence through a positive feedback loop with TP53. Is a TP53 downstream target gene that increases the stability of TP53 protein by promoting the ubiquitination and degradation of MDM2
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.