USE1 — Unconventional SNARE in the ER 1
USE1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
USE1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | Integrated Stress Response Stress | AKAP17A, ANKHD1, APBB3, C15orf39, CSF2RA, DDIT3, DDX39B, EMD +17 more | View in SCUBA |
About the gene
| Synonyms | D12, MDS032, p31, SLT1 |
|---|---|
| Chromosome | 19: 17215346-17219829 |
| Predicted location | Intracellular, Membrane |
| Essential gene | Yes |
| Protein class | Essential proteins, Predicted intracellular proteins, Predicted membrane proteins |
| Biological process | ER-Golgi transport, Protein transport, Transport |
Function
SNARE that may be involved in targeting and fusion of Golgi- derived retrograde transport vesicles with the ER
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.