WNT6 — Wnt family member 6
WNT6 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
WNT6's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Glial cells | Mature Glial Identity Neroprotection | BMP7, CHADL, CNTN1, MT3, PPP1R1B, PPP2R2B, SFRP5, TTYH1 +1 more | View in SCUBA |
About the gene
| Chromosome | 2: 218859805-218874233 |
|---|---|
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Predicted secreted proteins |
| Molecular function | Developmental protein |
| Biological process | Wnt signaling pathway |
Function
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. Together with CAV1 may promote chemoresistance of gastric cancer cells to DNA- damaging anthracycline drugs through the activation of the canonical Wnt receptor signaling pathway
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.