XPNPEP1 — X-prolyl aminopeptidase 1
XPNPEP1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
XPNPEP1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | Ubiquitin-Proteasome System Housekeeping | ACTR10, ADSS2, ATXN10, CAND1, CYRIB, DKC1, DPM1, EIF4E +18 more | View in SCUBA |
About the gene
| Synonyms | XPNPEP, XPNPEPL, XPNPEPL1 |
|---|---|
| Chromosome | 10: 109864766-109923553 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Predicted intracellular proteins |
| Molecular function | Aminopeptidase, Hydrolase, Metalloprotease, Protease |
Function
Metalloaminopeptidase that catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg- Pro-Pro. Contributes to the degradation of bradykinin.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.