SCUBA

ABCA13 — ATP binding cassette subfamily A member 13

ABCA13 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

ABCA13's module in each cell type

Cell typeModuleShares the module with
Hematopoietic progenitor cellsEarly Myeloid Progenitor
Myeloid development
ARID5B, CD34, GPRIN3, NCOA7, PRSS2, RXFP1, SETBP1
NeutrophilsmRNA Splicing Processing
Housekeeping
ATP2A3, EMB, FBXO9, LUC7L3, NKTR, OGT, PAXBP1, PNN +8 more

About the gene

SynonymsFLJ33876, FLJ33951
Chromosome7: 48171458-48647497
Predicted locationMembrane
Essential geneNo
Protein classPredicted membrane proteins

Function

May mediate the cholesterol and gangliosides transport from the plasma membrane to intracellular vesicles in an ATP hydrolysis dependent manner, thus playing a role in their internalization by endocytic retrograde transport and may also participate in the endocytosis of synaptic vesicle in cortical neurons

Human Protein Atlas · Open Targets

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.