ABTB1 — Ankyrin repeat and BTB domain containing 1
ABTB1 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ABTB1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Neutrophils | Neutrophil Differentiation Developmental | FRAT2, GCA, ICAM3, MANSC1, MNDA, MSL3, NFE2, QPCT +2 more | |
| Smooth muscle cells | Lipid Kinase Signaling Housekeeping | ARRDC4, CACNA1H, CBX7, CX3CL1, DGKD, DNTTIP2, FCHSD2, FYTTD1 +10 more | View in SCUBA |
About the gene
| Synonyms | BPOZ, Btb3, BTBD21, EF1ABP |
|---|---|
| Chromosome | 3: 127672935-127680926 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | Elongation factor |
| Biological process | Protein biosynthesis |
Function
May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.