FYTTD1 — Forty-two-three domain containing 1
FYTTD1 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
FYTTD1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Actin Cytoskeletal Remodeling Cytoskeletal | ACTR2, ANKRD11, ARPC4, CAP1, EIF4G1, G3BP1, GSPT1, IPO7 +8 more | View in SCUBA |
| Gamma-delta T cells | T Cell Exhaustion Exhaustion | ACADVL, ACSS1, ADSS2, B4GALT3, CDK11A, CHP1, CNOT2, CNOT8 +20 more | |
| Innate lymphoid cells | RNA Processing Mixed RNA processing & translation | AUP1, B3GAT3, CFDP1, CMTM3, DENR, EIF4H, FBXW5, FUCA1 +13 more | View in SCUBA |
| Macrophages | RNA Processing Regulation Housekeeping | ACBD3, AQR, ARCN1, BFAR, BNIP3L, CCNI, CCNK, DIS3 +15 more | View in SCUBA |
| Smooth muscle cells | Lipid Kinase Signaling Housekeeping | ABTB1, ARRDC4, CACNA1H, CBX7, CX3CL1, DGKD, DNTTIP2, FCHSD2 +10 more | View in SCUBA |
About the gene
| Synonyms | DKFZp761B1514, UIF |
|---|---|
| Chromosome | 3: 197737179-197787596 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | RNA-binding |
| Biological process | mRNA transport, Transport |
Function
Required for mRNA export from the nucleus to the cytoplasm. Acts as an adapter that uses the DDX39B/UAP56-NFX1 pathway to ensure efficient mRNA export and delivering to the nuclear pore. Associates with spliced and unspliced mRNAs simultaneously with ALYREF/THOC4
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.