ADK — Adenosine kinase
ADK belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ADK's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Naïve T Cell T cell maturation | AIF1, ARHGAP15, ARMH1, BACH2, CCR7, CNR2, DPYD, FAM117B +7 more | |
| Neutrophils | Myeloid Lipid Remodeling Developmental | AGPS, ATP8A1, ATP8B4, CLTCL1, DOP1B, ERG, GPD2, HNRNPLL +3 more |
About the gene
| Synonyms | AK |
|---|---|
| Chromosome | 10: 74151202-74709963 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins |
| Molecular function | Kinase, Transferase |
| Biological process | Purine salvage |
Function
Catalyzes the phosphorylation of the purine nucleoside adenosine at the 5' position in an ATP-dependent manner. Serves as a potential regulator of concentrations of extracellular adenosine and intracellular adenine nucleotides.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.