AHCTF1 — AT-hook containing transcription factor 1
AHCTF1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
AHCTF1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Monocytes | AMPK-FOXO Stress Response Stress | C15orf39, FOXO3, FURIN, IRF2BP2, JARID2, MIDN, PRKAG2, TLE3 | View in SCUBA |
About the gene
| Synonyms | ELYS |
|---|---|
| Chromosome | 1: 246839098-246931948 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Metabolic proteins, Predicted intracellular proteins, Transporters |
| Molecular function | DNA-binding |
| Biological process | Cell cycle, Cell division, mRNA transport, Protein transport, Translocation, Transport |
Function
Required for the assembly of a functional nuclear pore complex (NPC) on the surface of chromosomes as nuclei form at the end of mitosis. May initiate NPC assembly by binding to chromatin and recruiting the Nup107-160 subcomplex of the NPC. Also required for the localization of the Nup107-160 subcomplex of the NPC to the kinetochore during mitosis and for the completion of cytokinesis
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.